Joe Grove, Principal Investigator
I love viruses and that’s pretty much all you need to know…
I studied undergraduate virology at the University of Warwick before training for my PhD with Prof. Jane McKeating at the University of Birmingham; this is where I developed my curiosity for virus entry and antibody evasion. I followed this with a postdoc with Prof. Mark Marsh at the MRC Laboratory for Molecular Cell Biology; where I received a comprehensive training in microscopy. I am indebted to my supervisors for the opportunities they provided, thank you Jane and Mark. After this I joined the Institute of Immunity and Transplantation at UCL to establish independence. I secured a Sir Henry Dale Fellowship in 2015 and now I’m just getting on with some cool experiments.
Lucas Walker, Research Assistant
I graduated in 2015 with a Master's in Biochemistry from the University of Sheffield, where I undertook research projects in pathogenic bacteria. As a research technician in the Grove lab, my interest is in the mechanisms of cell entry by Hep C and the role played by antibody selection in the conflict between the virus and host. I am examining critical structural and functional components in both the viral glycoproteins E1 and E2 as well as in host cell receptors using mutagenesis, microscopy and viral pseudoparticle assays.
Lenka Stejskal, PhD Student
I graduated from the University of Huddersfield with BSc Biochemistry in 2015 and joined the interdisciplinary Wellcome Trust PhD Programme at UCL and Birkbeck the same year. My main research interests revolve around the antibody response to HCV. I am using a mixture of experimental and computational techniques to answer some of the most burning questions. What are the determinants of antibody-mediated neutralization of HCV? Why are a few people able to resolve the infection spontaneously when the majority cannot? Can this knowledge help to design a vaccine against HCV?